2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-W015213R
    Adenine monohydrochloride hemihydrate (Standard) 6055-72-7 98%
    Adenine monohydrochloride hemihydrate (Standard) is the analytical standard of Adenine monohydrochloride hemihydrate (HY-W015213). This product is intended for research and analytical applications. Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine monohydrochloride hemihydrate (Standard)
  • HY-W015300R
    Suberic acid (Standard) 505-48-6
    Suberic acid (Standard) is the analytical standard of Suberic acid. This product is intended for research and analytical applications. Suberic acid is an orally active crystalline dibasic acid. Suberic acid activates the Akt signaling pathway and regulates the expression of molecules related to the TGF-β and MAPK signaling pathways. Suberic acid inhibits skin dryness.
    Suberic acid (Standard)
  • HY-W015309R
    Decanoic acid (Standard) 334-48-5 98%
    Decanoic acid (Standard) is the analytical standard of Decanoic acid. This product is intended for research and analytical applications. Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy.
    Decanoic acid (Standard)
  • HY-W015422R
    1,5-Isoquinolinediol (Standard) 5154-02-9 98%
    1,5-Isoquinolinediol is a potent PARP inhibitor, with an IC50 of 0.18-0.37 μM. 1,5-Isoquinolinediol attenuates diabetes-induced NADPH oxidase-derived oxidative stress in retina.
    1,5-Isoquinolinediol (Standard)
  • HY-W015445R
    SD-169 (Standard) 1670-87-7 98%
    SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation.
    SD-169 (Standard)
  • HY-W015466R
    Acetylvaline (Standard) 96-81-1 98%
    Acetylvaline (Standard) is an analytical standard for acetylvaline (HY-W015466). This product is intended for research and analytical applications. Acetylvaline is an amino acid derivative that belongs to the N-acetylated amino acid family. Acetylvaline is detected in low levels in the urine of healthy individuals, but significant abnormal excretion is observed in the urine of individuals with maple syrup urine disease (MSUD). Acetylvaline can be used to detect MSUD.
    Acetylvaline (Standard)
  • HY-W015616R
    Benzylacetone (Standard) 2550-26-7 98%
    Benzylacetone (4-Penylbutan-2-one) (Standard) is the analytical standard of Benzylacetone (HY-W015616). This product is intended for research and analytical applications. Benzylacetone is an aromatic compound. Benzylacetone is a mushroom tyrosinase inhibitor with an IC50 of 2.8 mM, a Ki of 1.25 mM for monophenolase and an IC50 of 0.6 mM, a Ki of 0.39 mM for diphenolase. Benzylacetone inhibits free mushroom tyrosinase and enzyme-substrate complex. Benzylacetone acts as an appetite enhancer via olfactory stimulation, reduces spontaneous locomotor activity, induces weight gain. Benzylacetone exhibits repellent, fumigant, and contact toxicity against Tribolium castaneum adults.
    Benzylacetone (Standard)
  • HY-W015780R
    1,4-Dimethoxybenzene (Standard) 150-78-7 99.99%
    1,4-Dimethoxybenzene (Standard) is the analytical standard of 1,4-Dimethoxybenzene. This product is intended for research and analytical applications. 1,4-Dimethoxybenzene is an endogenous metabolite.
    1,4-Dimethoxybenzene (Standard)
  • HY-W015782R
    4-Ethylresorcinol (Standard) 2896-60-8 98%
    4-Ethylresorcinol (Standard) is the analytical standard of 4-Ethylresorcinol (HY-W015782). This product is intended for research and analytical applications. 4-Ethylresorcinol is a derivative of resorcinol and can serve as a substrate for tyrosinase. 4-Ethylresorcinol has anti-hyperpigmentation and antioxidant effects and can inhibit melanin synthesis. 4-Ethylresorcinol has potential whitening value.
    4-Ethylresorcinol (Standard)
  • HY-W015786R
    4-Ethoxyphenol (Standard) 622-62-8 98%
    L-Amoxicillin (Standard) is the analytical standard of L-Amoxicillin. This product is intended for research and analytical applications. L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application.
    4-Ethoxyphenol (Standard)
  • HY-W015806R
    3-Pyridineacetic acid (Standard) 501-81-5 98%
    3-Pyridineacetic acid (Standard) is an analytical standard for 3-Pyridineacetic acid (HY-W015806). This product is for research and analytical applications. 3-Pyridineacetic acid is an orally active nicotinic acid analog. 3-Pyridineacetic acid enhances cholesterol oxidation in rat liver mitochondria. 3-Pyridineacetic acid inhibits Triton-induced hypercholesterolemia in rats. 3-Pyridineacetic acid can be used in research related to hypercholesterolemia.
    3-Pyridineacetic acid (Standard)
  • HY-W015823R
    4-Hydroxybenzyl cyanide (Standard) 14191-95-8 98%
    4-Hydroxybenzyl cyanide is an endogenous metabolite.
    4-Hydroxybenzyl cyanide (Standard)
  • HY-W016480R
    4-Amino-L-phenylalanine (Standard) 943-80-6 98%
    4-Amino-L-phenylalanine is an endogenous metabolite.
    4-Amino-L-phenylalanine (Standard)
  • HY-W016482R
    3-(3-Methoxyphenyl)propionic acid (Standard) 10516-71-9 98%
    3-(3-Methoxyphenyl)propionic acid is an organic acid, naturally occurring human metabolite and excreted in human urine.
    3-(3-Methoxyphenyl)propionic acid (Standard)
  • HY-W016798R
    (S)-2-acetamido-4-amino-4-oxobutanoic acid (Standard) 4033-40-3 98%
    (S)-2-acetamido-4-amino-4-oxobutanoic acid (Standard) is an analytical standard for (S)-2-acetamido-4-amino-4-oxobutanoic acid (HY-W016798). This product is intended for research and analytical applications. (S)-2-acetamido-4-amino-4-oxobutanoic acid is a metabolite. (S)-2-acetamido-4-amino-4-oxobutanoic acid can be used in the research of decompensated liver cirrhosis.
    (S)-2-acetamido-4-amino-4-oxobutanoic acid (Standard)
  • HY-W016812R
    Orotic acid hydrate (Standard) 50887-69-9 98%
    Orotic acid (hydrate) (Standard) is the analytical standard of Orotic acid (hydrate) (HY-W016812). This product is intended for research and analytical applications. Orotic acid hydrate is an endogenous metabolite.
    Orotic acid hydrate (Standard)
  • HY-W016993R
    2,3,4-Trihydroxybenzoic acid (Standard) 610-02-6 98%
    2,3,4-Trihydroxybenzoic acid (Standard) is the analytical standard substance of 2,3,4-Trihydroxybenzoic acid. This product is used for research and analytical applications. 2,3,4-Trihydroxybenzoic acid is an α-amylase inhibitor with an IC50 of 17.30 mM against porcine α-amylase. 2,3,4-Trihydroxybenzoic acid increases cellular p21 and p27 protein levels. 2,3,4-Trihydroxybenzoic acid inhibits cancer cell growth and delays starch digestion to suppress postprandial hyperglycemia. 2,3,4-Trihydroxybenzoic acid can be used in research related to colorectal cancer, breast cancer and type 2 diabetes.
    2,3,4-Trihydroxybenzoic acid (Standard)
  • HY-W017007R
    3-Methyl-L-histidine (Standard) 368-16-1
    3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin.
    3-Methyl-L-histidine (Standard)
  • HY-W017113R
    2-Mercaptobenzothiazole (Standard) 149-30-4 98%
    2-Mercaptobenzothiazole (Standard) is the analytical standard of 2-Mercaptobenzothiazole. This product is intended for research and analytical applications. 2-Mercaptobenzothiazole is an endogenous metabolite.
    2-Mercaptobenzothiazole (Standard)
  • HY-W017163R
    7-Methylxanthine (Standard) 552-62-5 98%
    7-Methylxanthine (Standard) is the analytical standard of 7-Methylxanthine. This product is intended for research and analytical applications. 7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity.
    7-Methylxanthine (Standard)
Cat. No. 상품명 / Synonyms Application Reactivity